If you are looking for high-quality products, please feel free to contact us and send an inquiry, email: brad@ihpa.net
Potassium bromide is a white crystalline salt, reminiscent of sodium chloride. It is a very hygroscopic and deliquescent compound, and is readily soluble in water, as well as in many polar organic solvents (including glycerol, ethylene glycol, liquid ammonia, hot ethanol, and acetone).
When dissolved in water, KBr dissociates completely into ions of potassium, K+, and bromine, Br-. These ions are then surrounded by water molecules to form a surface layer.
It is used as a redox reagent, in the production of photographic-grade silver bromide, and as a shape-control agent in metal nanocrystal formation. It is also a common source of bromine ions used in double displacement reactions and salt metathesis reactions.
As an anti-seizure agent, it inhibits the entry of chloride ions into the brain tissues. It is effective in treating early-onset epilepsy, in particular those characterized by generalized tonic-clonic seizures and/or alternating hemi-grand mal, and in those for whom other antiepileptic agents are ineffective.
The long half-life of KBr means that it will take some time to reduce serum levels when stopping treatment. This may cause side effects such as sedation, polydipsia and mild paresis.
In animals, potassium bromide can be administered as an adjunct to phenobarbital therapy for seizures. Dosages of 20-40 mg/kg/day, PO, either as one dose or divided into two or more doses, may be used.
In addition, dogs on a high salt diet may require dosages of 50-80 mg/kg/day to maintain adequate serum concentrations. Since resorption of KBr through renal tubules is dependent on chloride intake, dogs receiving bromide must maintain a stable chloride intake.
Inquiry us